WebJan 10, 2024 · In this particular case, even though total serum protein was within the normal range, the elevated globulin would prompt a request for further testing. About Serum Protein Electrophoresis SPEP is specifically used to separate and analyze amounts of the five main blood serum proteins: albumin, and the four types of globulins – alpha 1 globulin ... WebMay 4, 2012 · Raised serum globulin or total protein, or both, is often the first indication of the presence of a paraprotein. The level of globulin in the serum is derived by subtracting the albumin concentration from the total protein. All globulins are produced by plasma cells in the bone marrow.
A/G Ratio in Acute Ischemic Stroke JIR
WebHigh globulin levels usually indicate infection, immune disorders, or inflammatory disease. These conditions typically include leukemia, rheumatoid arthritis, liver disease, kidney disease, syphilis, ulcerative colitis, and autoimmune diseases. WebThe total serum protein test measures all the proteins in your blood. It can also check the amount of albumin you have compared to globulin, or what’s called your “A/G ratio.” … cryptococcus cxr
What does it mean when your alpha 2 globulin is high?
WebOct 7, 2024 · Globulin, as a major serum protein component, is synthesized and secreted mostly by the liver and plasma cells in response to inflammatory and infective reactions. Antibodies and inflammatory cytokines are the two major components of globulin [ 10 ]. WebApr 15, 2024 · 16. CALCULATION OF GLOBULINS Serum Globulins = [Serum Total Proteins – Serum Albumin] Normal serum Globulins range is 2.5 – 3.5 gm% Increased levels are seen in multiple myeloma and chronic infections In the above conditions, the A/G ratio is either lowered or completely reversed By Dr. Santhosh Kumar N/ Dept.of Biochem. 17. WebSerum protein electrophoresis (SPEP or SPE) is a laboratory test that examines specific proteins in the blood called globulins. The most common indications for a serum protein electrophoresis test are to diagnose or monitor multiple myeloma, a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy … cryptococcus cytospin